Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003 | 0.87 | TSHR (0.79) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL4908158 | 0.86 | TSHR (0.72) | TSHRCA1CA2CA9FOLH1 | |
| Acetic Acid SCHEMBL28245857 | 0.85 | TSHR (0.71) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL28370887 | 0.85 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.85 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL7759867 | 0.84 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL69041 | 0.84 | TSHR (1.00) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL29580520 | 0.84 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL2292722 | 0.84 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL28115 | 0.82 | FOLH1 (0.61) | TSHRCA1CA2CA9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280983-B9 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM (FR) | 2021-06-09 | — | — | EP | disclosed |
| US-8486897-B2 | C-aryl glycoside compounds for the treatment of diabetes and obesity | TFCHEM (FR) | 2013-07-16 | — | — | US | disclosed |
| US-8486897-B2 | C-aryl glycoside compounds for the treatment of diabetes and obesity | TFCHEM (FR) | 2013-07-16 | — | — | US | disclosed |
| EP-2280983-B1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM (FR) | 2013-03-13 | — | — | EP | disclosed |
| US-20110034402-A1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM | 2011-02-10 | — | — | US | disclosed |
| US-20110034402-A1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM | 2011-02-10 | — | — | US | disclosed |
| WO-2009121939-A2 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | TFCHEM (FR) | 2009-10-08 | — | — | WO | disclosed |
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034402-A1 | C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY | SLC5A2, SLC5A1, GPR119 | TSHR 1386/4885CA1 3447/4885CA2 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.