Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717135 | 0.94 | MAPT (0.50) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL28802564 | 0.88 | MAPT (0.48) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL9578706 | 0.78 | MAPT (0.50) | MAPTMAPK1HTTALDH1A1TDP1 | |
| SCHEMBL4725792 | 0.78 | APEX1 (0.44) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL9061250 | 0.78 | MAPT (0.52) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL8285443 | 0.78 | MAPT (0.71) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL10901421 | 0.77 | MAPT (0.75) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL10863927 | 0.72 | MAPT (0.50) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL3420496 | 0.72 | MAPT (0.58) | MAPTKDM4EMAPK1RAB9AHSP90AA1 | |
| SCHEMBL4463980 | 0.71 | HKDC1 (0.67) | MAPTKDM4EMAPK1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263281-B1 | MULTIPLE GENE EXPRESSION FOR ENGINEERING NOVEL PATHWAYS AND HYPEREXPRESSION OF FOREIGN PROTEINS IN PLANTS | UNIV AUBURN (US) | 2012-04-11 | — | — | EP | disclosed |
| US-20080241916-A1 | Multiple Gene Expression For Engineering Novel Pathways And Hyperexpression Of Foreign Proteins in Plants | DANIELL HENRY | 2008-10-02 | — | — | US | disclosed |
| US-7294506-B2 | Tobacco chloroplast transformation vectors comprising a multi-gene operon encoding a biopharmaceutical protein and a chaperonin | UNIVERSITY CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2007-11-13 | — | — | US | disclosed |
| US-20040210966-A1 | Multiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2004-10-21 | — | — | US | disclosed |
| EP-1263281-A4 | MULTIPLE GENE EXPRESSION FOR ENGINEERING NOVEL PATHWAYS AND HYPEREXPRESSION OF FOREIGN PROTEINS IN PLANTS | UNIV AUBURN (US) | 2004-07-07 | — | — | EP | disclosed |
| US-20030041353-A1 | Mutiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants | UNIVERSITY CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2003-02-27 | — | — | US | disclosed |
| EP-1263281-A1 | MULTIPLE GENE EXPRESSION FOR ENGINEERING NOVEL PATHWAYS AND HYPEREXPRESSION OF FOREIGN PROTEINS IN PLANTS | AUBURN UNIVERSITY (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001064024-A1 | MULTIPLE GENE EXPRESSION FOR ENGINEERING NOVEL PATHWAYS AND HYPEREXPRESSION OF FOREIGN PROTEINS IN PLANTS | AUBURN UNIVERSITY (US) | 2001-09-07 | — | — | WO | disclosed |
| EP-0482789-B1 | Benzoquinone compounds | ZENECA LTD (GB) | 1996-01-03 | — | — | EP | disclosed |
| US-5283355-A | Benzoquinone compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-01 | — | — | US | disclosed |
| EP-0355492-B1 | REACTIVE DYES | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5138054-A | Colorfastness, photostability; red dye | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0482789-A2 | Benzoquinone compounds | ZENECA LIMITED (GB) | 1992-04-29 | — | — | EP | disclosed |
| EP-0355492-A1 | Reactive dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |