Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aurantiogliocladin SCHEMBL487583 | 0.81 | MAPT (0.50) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL9061250 | 0.80 | MAPT (0.52) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL4908282 | 0.78 | MAPT (0.48) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL9655485 | 0.75 | CDC25A (0.64) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL1392670 | 0.74 | CES1 (0.47) | IDO1MAPTKDM4ERAB9ACDC25B | |
| SCHEMBL1717135 | 0.74 | MAPT (0.50) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL28802564 | 0.73 | MAPT (0.48) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL13453022 | 0.72 | CES2 (0.53) | IDO1MAPTKDM4EMAPK1TDP1 | |
| SCHEMBL3420496 | 0.71 | MAPT (0.58) | APEX1IDO1MAPTKDM4ERAB9A | |
| SCHEMBL12592463 | 0.70 | CDC25A (0.58) | APEX1IDO1MAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-10 | — | — | US | disclosed |
| WO-2008019196-A2 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHSIS OF UBIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-14 | — | — | WO | disclosed |
| US-20080039642-A1 | Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones | ZYMES, LLC | 2008-02-14 | — | — | US | disclosed |
| WO-2006032425-A2 | A PRACTICAL, COST-EFFECTIVE SYNTHESIS OF CHLOROMETHYLATED 1,4-BENZOQUINONES | ZYMES, LLC (US) | 2006-03-30 | — | — | WO | disclosed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | NDUFA10, NDUFB10, NDUFV1 | APEX1 338/4885IDO1 937/4885MAPT 3856/4885 |
| US-20080039642-A1 | Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones | NDUFA10, NDUFB10, NDUFA5 | APEX1 1496/4885IDO1 1761/4885MAPT 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.