Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17782172 | 0.85 | GAA (0.43) | KDM4EGAAGLAPDE3BPDE3A | |
| SCHEMBL3092320 | 0.83 | KDM4E (0.39) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3081585 | 0.78 | HSP90AA1 (0.35) | KDM4EMAPTALDH1A1 | |
| SCHEMBL3092324 | 0.74 | — | — | |
| SCHEMBL17782170 | 0.74 | HSD17B1 (0.41) | KDM4EGAAGLAPDE3BPDE3A | |
| SCHEMBL3075472 | 0.73 | KDM4E (0.54) | KDM4EGAAGLAMAPTCFTR | |
| SCHEMBL31185924 | 0.73 | PDE3B (0.53) | KDM4EGAAGLAPDE3BPDE3A | |
| SCHEMBL17782171 | 0.73 | HSD17B1 (0.55) | KDM4EGAAGLAPDE3BPDE3A | |
| SCHEMBL4898556 | 0.72 | CFTR (0.46) | KDM4EGAAGLAPDE3BPDE3A | |
| SCHEMBL4906582 | 0.72 | SOS1 (0.44) | KDM4EGAAGLAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | KDM4E 740/4885GAA 3433/4885GLA 1905/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | KDM4E 826/4885GAA 3296/4885GLA 2012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.