Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12448089 | 0.77 | CPB2 (0.39) | CPB2POLBSYK | |
| SCHEMBL28784470 | 0.76 | — | — | |
| SCHEMBL4908884 | 0.75 | CPB2 (0.41) | CPB2POLBCPB1 | |
| SCHEMBL27654362 | 0.75 | CPB2 (0.38) | CPB2POLB | |
| SCHEMBL12224159 | 0.75 | CPB2 (0.38) | CPB2POLB | |
| SCHEMBL19867832 | 0.73 | CPB2 (0.54) | CPB2POLBCPB1 | |
| SCHEMBL18250233 | 0.72 | CPB2 (0.37) | CPB2POLB | |
| SCHEMBL22387919 | 0.71 | IRAK4 (0.39) | CPB2POLBSYKWDR5 | |
| SCHEMBL5533170 | 0.71 | RPS6KB1 (0.38) | CPB2POLB | |
| SCHEMBL25235849 | 0.69 | CPB2 (0.47) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194822-A1 | Heating 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline with ammonia in a polar aprotic solvent to produce imiquimod; purification; industrial scale; dechlorination; precipitation, crystallization, slurrying, washing in a suitable solvent, filtration through a packed-bed column, dissolution in solvent | CHEMAGIS LTD. (IL) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194822-A1 | Heating 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline with ammonia in a polar aprotic solvent to produce imiquimod; purification; industrial scale; dechlorination; precipitation, crystallization, slurrying, washing in a suitable solvent, filtration through a packed-bed column, dissolution in solvent | IMPDH1, IDO1, IPO4 | CPB2 3906/4885POLB 628/4885SYK 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.