Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329784 | 0.79 | — | — | |
| SCHEMBL20702575 | 0.75 | ALDH1A1 (0.37) | CPB2 | |
| SCHEMBL23118112 | 0.75 | ALDH1A1 (0.37) | CPB2 | |
| SCHEMBL23118113 | 0.75 | ALDH1A1 (0.37) | CPB2 | |
| SCHEMBL23139176 | 0.73 | KMT2A (0.36) | CPB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12448089 | 0.72 | CPB2 (0.39) | RPS6KB1CPB2POLB | |
| SCHEMBL20713602 | 0.72 | MEN1 (0.30) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL24128290 | 0.71 | TBXAS1 (0.38) | CPB2KDM4EMEN1KMT2A | |
| SCHEMBL2390897 | 0.71 | IRAK4 (0.33) | IRAK4CPB2 | |
| SCHEMBL4908884 | 0.71 | CPB2 (0.41) | RPS6KB1CPB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863770-A2 | RING CLOSING AND RELATED METHODS AND INTERMEDIATES | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006121528-A2 | RING CLOSING AND RELATED METHODS AND INTERMEDIATES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-11-16 | — | — | WO | disclosed |