Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 15/20 | 0.79 |
| ▸ | BCHE | P06276 | 5/20 | 0.75 |
| ▸ | ACHE | P22303 | 5/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.75 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.75 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.75 |
| ▸ | RECQL | P46063 | 2/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | THPO | P40225 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918881 | 0.97 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918374 | 0.97 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918894 | 0.97 | CHRM2 (0.80) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL10873043 | 0.93 | CHRM2 (0.85) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4373386 | 0.90 | CHRM2 (0.97) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918396 | 0.89 | CHRM2 (0.79) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4913173 | 0.87 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL4918181 | 0.87 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 | |
| SCHEMBL5035489 | 0.87 | CHRM2 (0.83) | CHRM2BCHEACHECHRM4CHRM5 | |
| Methoctramine SCHEMBL11982296 | 0.86 | CHRM2 (1.00) | CHRM2BCHEACHECHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462141-B1 | NOVEL AZAHETEROCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-09-27 | — | — | EP | claimed |
| US-9023847-B2 | Azaheterocyclic compounds | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | US | claimed |
| EP-2462141-A1 | NOVEL AZAHETEROCYCLIC COMPOUNDS | Merck Patent GmbH (DE) | 2012-06-13 | — | — | EP | claimed |
| EP-3390483-B1 | ENCAPSULATION | PROCTER & GAMBLE (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3368207-B1 | ENCAPSULATION | ENCAPSYS LLC (US) | 2021-12-01 | — | — | EP | disclosed |
| US-10864167-B2 | Encapsulation | THE PROCTER & GAMBLE COMPANY (US) | 2020-12-15 | — | — | US | disclosed |
| EP-3390483-A1 | ENCAPSULATION | The Procter and Gamble Company (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-3368207-A1 | ENCAPSULATION | ENCAPSYS, LLC (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20180235893-A1 | ENCAPSULATION | THE PROCTER & GAMBLE COMPANY | 2018-08-23 | — | — | US | disclosed |
| US-9937477-B2 | Encapsulation | WATERTITE PRODUCTS, INC. | 2018-04-10 | — | — | US | disclosed |
| CN-107708853-A | Encapsulating | 恩盖普有限公司 | 2018-02-16 | — | — | CN | disclosed |
| US-20170113200-A1 | Encapsulation | Encapsys,LLC (US) | 2017-04-27 | — | — | US | disclosed |
| US-9023847-B2 | Azaheterocyclic compounds | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-8552078-B2 | Non-fugitive tertiary amine catalyst and alkylated polyamine crosslinking additives; aging resistance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| CN-101168601-B | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM | 2013-03-06 | — | — | CN | disclosed |
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | US | disclosed |
| CN-101168601-A | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20080090922-A1 | Crosslinkers for improving stability of polyurethane foams | EVONIK OPERATIONS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | PCNA, MCL1, MYC | CHRM2 4710/4885BCHE 4539/4885ACHE 4885/4885 |
| US-20180235893-A1 | ENCAPSULATION | ACR, ACMSD, SAMM50 | CHRM2 1120/4885BCHE 1469/4885ACHE 1955/4885 |
| US-10864167-B2 | Encapsulation | ACR, MPHOSPH6, ACMSD | CHRM2 993/4885BCHE 1742/4885ACHE 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.