Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909349 | 1.00 | GRM5 (0.42) | GRM5CHRNB4CHRNA3MEN1ALOX12 | |
| Trifluoroacetic Acid SCHEMBL3879936 | 0.92 | GRM5 (0.41) | GRM5CHRNB4CHRNA3MEN1ALOX12 | |
| Trifluoroacetic Acid SCHEMBL3879928 | 0.92 | GRM5 (0.41) | GRM5CHRNB4CHRNA3MEN1ALOX12 | |
| SCHEMBL4911752 | 0.81 | NPC1 (0.39) | MEN1KMT2AMLNRCYP2D6LMNA | |
| SCHEMBL4911748 | 0.81 | NPC1 (0.39) | MEN1KMT2AMLNRCYP2D6LMNA | |
| Trifluoroacetic Acid SCHEMBL3872908 | 0.74 | NPC1 (0.39) | KDM4EMLNRSMN1; SMN2NPC1GRM2 | |
| Trifluoroacetic Acid SCHEMBL3872911 | 0.74 | NPC1 (0.39) | KDM4EMLNRSMN1; SMN2NPC1GRM2 | |
| SCHEMBL3879932 | 0.74 | GRM5 (0.37) | GRM5CHRNB4CHRNA3MEN1ALOX12 | |
| SCHEMBL4919703 | 0.74 | GRM2 (0.39) | GRM2 | |
| SCHEMBL4919710 | 0.74 | GRM2 (0.39) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167342-A1 | Heteroaryl-Substituted Amides Comprising An Unsaturated Or Cyclic Linker Group, And Their Use As Pharmaceuticals | SANOFI-AVENTIS (FR) | 2008-07-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167342-A1 | Heteroaryl-Substituted Amides Comprising An Unsaturated Or Cyclic Linker Group, And Their Use As Pharmaceuticals | TBXAS1, PTGIS, NOS2 | GRM5 1904/4885CHRNB4 3109/4885CHRNA3 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.