Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | BTN3A1 | O00481 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013663 | 0.96 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1BTN3A1LMNA | |
| SCHEMBL5372580 | 0.96 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1BTN3A1LMNA | |
| Formic Acid SCHEMBL9013905 | 0.89 | ALDH1A1 (0.53) | ALDH1A1ALOX15PTPN1BTN3A1LMNA | |
| SCHEMBL1073133 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ALOX15PTPN1BTN3A1FNTA | |
| SCHEMBL1073135 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ALOX15PTPN1BTN3A1FNTA | |
| SCHEMBL9270948 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ALOX15PTPN1BTN3A1FNTA | |
| SCHEMBL3083781 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ALOX15PTPN1BTN3A1FNTA | |
| SCHEMBL9270945 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ALOX15PTPN1BTN3A1FNTA | |
| SCHEMBL21856602 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 | |
| SCHEMBL11790751 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200733-A1 | Processes For The Preparation Of Purified Solanesol, Solanesyl Bromide & Solanesyl Acetone | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2008-08-21 | — | — | US | disclosed |
| EP-1904513-A2 | IMPROVED PROCESSES FOR THE PREPARATION OF PURIFIED SOLANESOL, SOLANESYL BROMIDE AND SOLANESYL ACETONE | Nicholas Piramal India Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007004090-A2 | IMPROVED PROCESSES FOR THE PREPARATION OF PURIFIED SOLANESOL, SOLANESYL BROMIDE AND SOLANESYL ACETONE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200733-A1 | Processes For The Preparation Of Purified Solanesol, Solanesyl Bromide & Solanesyl Acetone | NDUFB10, SQOR, ACAA2 | ALDH1A1 936/4885ALOX15 918/4885PTPN1 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.