Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254265 | 0.76 | — | — | |
| SCHEMBL12222294 | 0.76 | PAOX (0.42) | ALDH1A1 | |
| SCHEMBL21417322 | 0.75 | TSHR (0.42) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL27795217 | 0.73 | GAA (0.35) | TSHRTHRBGAA | |
| SCHEMBL13233722 | 0.72 | — | — | |
| SCHEMBL530709 | 0.72 | — | — | |
| SCHEMBL295441 | 0.72 | GAA (0.34) | GAA | |
| SCHEMBL14301879 | 0.72 | — | — | |
| SCHEMBL9212311 | 0.71 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL9207554 | 0.71 | TSHR (0.38) | TSHRTHRBDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105567-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2012-01-31 | — | — | US | disclosed |
| US-8105567-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2012-01-31 | — | — | US | disclosed |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-04-07 | — | — | US | disclosed |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-04-07 | — | — | US | disclosed |
| US-7893223-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2011-02-22 | — | — | US | disclosed |
| US-7893223-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING S.P.A. (IT) | 2011-02-22 | — | — | US | disclosed |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | BRACCO IMAGING S.P.A (IT) | 2010-03-18 | — | — | US | disclosed |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | BRACCO IMAGING S.P.A (IT) | 2010-03-18 | — | — | US | disclosed |
| EP-1904460-A1 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING S.p.A. (IT) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006136564-A9 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING SPA (IT) | 2008-02-07 | — | — | WO | disclosed |
| WO-2006136564-A9 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING SPA (IT) | 2008-02-07 | — | — | WO | disclosed |
| WO-2006136564-A1 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING S.P.A. (IT) | 2006-12-28 | — | — | WO | disclosed |
| US-20060034773-A1 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060034773-A1 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | SSTR3, MB, CA13 | TSHR 5/4885THRB 88/4885CYP19A1 1112/4885 |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | CD99, CD209, PRMT9 | TSHR 10/4885THRB 85/4885CYP19A1 861/4885 |
| US-20100069628-A1 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy | CD99, MB, HBZ | TSHR 11/4885THRB 22/4885CYP19A1 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.