SCHEMBL915610

SCHEMBL915610

CO[Si](CNCCCN(C)C)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
PAOX Q6QHF9 1/20 0.39
TERT O14746 1/20 0.38
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
DPP7 Q9UHL4 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
KDM4E B2RXH2 3/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
ALOX15 P16050 1/20 0.33
LMNA P02545 1/20 0.31
PRMT3 O60678 1/20 0.31
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PRMT1 Q99873 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195990 0.87 CYP2C9 (0.43) TDP1TERTCYP2C9CYP2C19ALDH1A1
SCHEMBL22323282 0.82 TDP1 (0.50) TDP1PAOXTERTCYP2C9CYP2C19
SCHEMBL555645 0.76 TSHR (0.46) CYP2C19ALDH1A1TSHRKMT2AMEN1
SCHEMBL14681200 0.76 LMNA (0.35) LMNA
SCHEMBL8380350 0.74 CA12 (0.46) TDP1PAOXCYP2C9CYP2C19ALDH1A1
SCHEMBL15859 0.74 TDP1 (0.75) TDP1PAOXTERTCYP2C9CYP2C19
SCHEMBL8083063 0.73 CYP2C9 (0.48) TDP1PAOXCYP2C9CYP2C19ALDH1A1
SCHEMBL131935 0.73 CA12 (0.43) TDP1CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL11141356 0.72 TSHR (0.50) ALDH1A1TSHRLMNA
SCHEMBL4024130 0.72 TSHR (0.50) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260543-A Silicon ether of silane coupling polyether and preparation method and application thereof 佛山市南海大田化学有限公司 2022-11-01 CN claimed
CN-115155113-A Structure for organic silicon defoaming agent and synthetic method thereof 佛山市南海大田化学有限公司 2022-10-11 CN claimed
CN-114316299-A Method for improving stability of organic silicon emulsion 南京瑞思化学技术有限公司 2022-04-12 CN claimed
CN-114316610-A Preparation method of organic silicon emulsion 南京瑞思化学技术有限公司 2022-04-12 CN claimed
CN-114307260-A Preparation method of polyether composition 南京瑞思化学技术有限公司 2022-04-12 CN claimed
CN-115260543-A Silicon ether of silane coupling polyether and preparation method and application thereof 佛山市南海大田化学有限公司 2022-11-01 CN disclosed
CN-115155113-A Structure for organic silicon defoaming agent and synthetic method thereof 佛山市南海大田化学有限公司 2022-10-11 CN disclosed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN disclosed
CN-114316299-A Method for improving stability of organic silicon emulsion 南京瑞思化学技术有限公司 2022-04-12 CN disclosed
CN-114316610-A Preparation method of organic silicon emulsion 南京瑞思化学技术有限公司 2022-04-12 CN disclosed
CN-114307260-A Preparation method of polyether composition 南京瑞思化学技术有限公司 2022-04-12 CN disclosed
CN-114316296-A Preparation method of water-based organic silicon composition 南京瑞思化学技术有限公司 2022-04-12 CN disclosed
WO-2006119916-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2006-11-16 WO disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed
US-7126020-B2 Reactions rapidly complete or proceeds at low temperature such as room temperature; highly viscous and stable products with Si C-bonded radicals containing basic nitrogen WACKER CHEMIE AG (DE) 2006-10-24 US disclosed
EP-1541615-B1 Method for the production of highly viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2006-03-22 EP disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed
US-20050131243-A1 Process for preparing highly viscous organopolysiloxanes WACKER-CHEMIE GMBH (DE) 2005-06-16 US disclosed
EP-1541615-A1 Method for the production of highly viscous organopolysiloxanes Wacker-Chemie GmbH (DE) 2005-06-15 EP disclosed