SCHEMBL22323282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8083063	0.92	CYP2C9 (0.48)	TDP1PAOXKDM4EALDH1A1MEN1
	SCHEMBL49693	0.85	LMNA (0.39)	ALDH1A1MEN1KMT2ACYP2C19TSHR
	SCHEMBL29534835	0.83	LMNA (0.38)	TDP1ALDH1A1MEN1KMT2ACYP2C19
	SCHEMBL4624700	0.83	LMNA (0.38)	TDP1ALDH1A1MEN1KMT2ACYP2C19
	SCHEMBL48137	0.83	LMNA (0.38)	TDP1ALDH1A1MEN1KMT2ACYP2C19
	SCHEMBL1931026	0.83	LMNA (0.38)	TDP1ALDH1A1MEN1KMT2ACYP2C19
	SCHEMBL27674	0.83	ALDH1A1 (0.43)	TDP1KDM4EALDH1A1TSHRDNM1
	Ammonia Solution, Strong SCHEMBL5681835	0.83	LMNA (0.38)	ALDH1A1MEN1KMT2ACYP2C19TSHR
	SCHEMBL7911598	0.82	TDP1 (0.48)	TDP1PAOXKDM4EALDH1A1MEN1
	SCHEMBL10481559	0.82	DNM1 (0.42)	PAOXKDM4EALOX15TSHRDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.