SCHEMBL9505652

SCHEMBL9505652

CO[SiH](Cc1ccccc1)OC.[SiH4]

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
LTA4H P09960 1/20 0.40
TSHR P16473 2/20 0.39
CALM1 P0DP23 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
IDO1 P14902 2/20 0.36
ALDH1A1 P00352 1/20 0.36
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49102 0.98 TP53 (0.42) TP53LTA4HTSHRCALM1CA4
SCHEMBL8830313 0.91 LTA4H (0.38) TP53LTA4HTSHRCALM1IDO1
Dimethylamine SCHEMBL7748343 0.91 LTA4H (0.42) TP53LTA4HTSHRCALM1IDO1
SCHEMBL3815801 0.83 TP53 (0.39) TP53LTA4HTSHRCALM1IDO1
SCHEMBL19809259 0.83 LTA4H (0.39) TP53LTA4HTSHRCA4ALDH1A1
SCHEMBL15455621 0.82 LTA4H (0.32) TP53LTA4HTSHR
SCHEMBL19809244 0.80 TP53 (0.37) TP53LTA4HTSHRALDH1A1
SCHEMBL20658040 0.80 LTA4H (0.33) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL29215801 0.78 TP53 (0.32) TP53LTA4H
SCHEMBL8440990 0.78 TSHR (0.32) TP53LTA4HTSHRIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274101-B1 RESTORING STRANDED CONDUCTOR ELECTRICAL DISTRIBUTION CABLE DOW CORNING CORPORATION (US) 1993-06-09 EP disclosed
US-4766011-A TREATING INTERSTICLES WITH AROMATIC RADICAL CONTAINING SILANE DOW CORNING CORPORATION (US) 1988-08-23 US disclosed
EP-0274101-A2 Restoring stranded conductor electrical distribution cable DOW CORNING CORPORATION (US) 1988-07-13 EP disclosed