Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49102 | 0.93 | TP53 (0.42) | LTA4HKDM4ECYP3A4MAPTCALM1 | |
| SCHEMBL9505652 | 0.91 | TP53 (0.40) | LTA4HCALM1TP53TSHRIDO1 | |
| SCHEMBL8830313 | 0.87 | LTA4H (0.38) | LTA4HKDM4ECYP3A4MAPTCALM1 | |
| SCHEMBL19809259 | 0.79 | LTA4H (0.39) | LTA4HKDM4ESIGMAR1TP53MEN1 | |
| SCHEMBL3815801 | 0.79 | TP53 (0.39) | LTA4HMAPTTAAR1CALM1LMNA | |
| SCHEMBL15455621 | 0.79 | LTA4H (0.32) | LTA4HTP53TSHR | |
| SCHEMBL3009952 | 0.77 | LTA4H (0.41) | LTA4HKDM4ECYP3A4MAPTTAAR1 | |
| SCHEMBL20658040 | 0.76 | LTA4H (0.33) | LTA4HKDM4ETAAR1CALM1SIGMAR1 | |
| SCHEMBL19809244 | 0.76 | TP53 (0.37) | LTA4HCYP3A4MAPTLMNATP53 | |
| SCHEMBL29215801 | 0.75 | TP53 (0.32) | LTA4HTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727443-B1 | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORP (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5807938-A | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0727443-A1 | Catalyst for olefin polymerization and process for producing olefin polymers | Tosoh Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |