Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264053 | 0.91 | MEN1 (0.56) | CYP11B1CYP11B2KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL18850044 | 0.89 | CYP11B1 (0.50) | CYP11B1CYP11B2METAP2METAP1ENPP3 | |
| SCHEMBL15460383 | 0.86 | CYP11B2 (0.56) | CYP11B1CYP11B2METAP2METAP1ENPP3 | |
| SCHEMBL4901225 | 0.85 | CYP11B2 (0.49) | CYP11B1CYP11B2METAP2METAP1ENPP3 | |
| SCHEMBL5647023 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2METAP2METAP1ENPP3 | |
| SCHEMBL11518482 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2METAP2METAP1ENPP3 | |
| SCHEMBL19309835 | 0.84 | CYP11B2 (0.55) | CYP11B1CYP11B2METAP2ENPP3KDM4E | |
| SCHEMBL4905901 | 0.79 | TDP1 (0.62) | CYP11B1CYP11B2KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL31301361 | 0.79 | SCN10A (0.51) | CYP11B1CYP11B2SMN1; SMN2ALDH1A1CHEK1 | |
| SCHEMBL4907728 | 0.78 | PIM1 (0.46) | CYP11B1CYP11B2ENPP3ENPP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040718-B2 | Hybrid host materials for electrophosphorescent devices | THE UNIVERSITY OF ROCHESTER (US) | 2015-05-26 | — | — | US | disclosed |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | THE UNIVERSITY OF ROCHESTER | 2010-07-22 | — | — | US | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | CYP4X1, CYP4F3, CYP1A2 | CYP11B1 18/4885CYP11B2 6/4885METAP2 4179/4885 |
| US-20100184942-A1 | Hybrid Host Materials For Electrophosphorescent Devices | SLC29A2, SLC43A3, SLC29A1 | CYP11B1 4014/4885CYP11B2 3759/4885METAP2 1596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.