Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR5A | P47898 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 5/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930517 | 0.88 | KDM4E (0.51) | ITGB1ITGA4MEN1KMT2APOLB | |
| SCHEMBL4925114 | 0.79 | MEN1 (0.42) | ITGB1ITGA4MEN1KMT2APOLB | |
| SCHEMBL7530457 | 0.73 | ITGB1 (0.43) | ITGB1ITGA4MEN1KMT2APOLB | |
| SCHEMBL9509511 | 0.69 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1644001 | 0.69 | CHRM2 (0.64) | ALDH1A1HPGDHTR1AMAPT | |
| SCHEMBL7536229 | 0.68 | CRHR1 (0.44) | ITGB1ITGA4MEN1KMT2AALDH1A1 | |
| SCHEMBL22721651 | 0.68 | ITGB1 (0.46) | ITGB1ITGA4MEN1KMT2AALDH1A1 | |
| SCHEMBL10437520 | 0.67 | ALDH1A1 (0.46) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL13918748 | 0.67 | GAA (0.41) | ITGB1ITGA4ALDH1A1KDM4EMAPT | |
| SCHEMBL24485285 | 0.67 | CYP1A2 (0.39) | ITGB1ITGA4MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234266-A1 | Squaric Acid Derivatives II | MERCK PATENT GESELLSCHAFT (DE) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234266-A1 | Squaric Acid Derivatives II | CHEK2, CHEK1, SGK3 | ITGB1 4524/4885ITGA4 4722/4885MEN1 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.