Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437519 | 0.84 | HDAC4 (0.49) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL22343536 | 0.76 | HNF4A (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10437520 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL22343599 | 0.75 | ELANE (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL27632073 | 0.75 | MEN1 (0.62) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL30335989 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL7150727 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL14438404 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11021178 | 0.73 | MEN1 (0.66) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL10942597 | 0.73 | MEN1 (0.63) | MEN1KMT2AKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396828-B1 | UNSYMMETRICAL SQUARAINE COMPOSITIONS AND PHOTOCONDUCTIVE IMAGING MEMBERS USING SUCH COMPOSITIONS | XEROX CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5030537-A | Photoconductive unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0396828-A1 | Unsymmetrical squaraine compositions and photoconductive imaging members using such compositions | XEROX CORPORATION (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4922018-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| US-4886722-A | Photoconductive imaging members with unsymmetrical squaraine compositions | XEROX CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |