SCHEMBL491144

SCHEMBL491144

C=C(C)C(=O)N(CCc1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GLA P06280 2/20 0.43
TSHR P16473 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
HPGD P15428 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
CHRM2 P08172 1/20 0.42
TSPO P30536 1/20 0.42
CHRM5 P08912 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28078011 0.83 NPC1 (0.56) ALDH1A1SMN1; SMN2MEN1KMT2AGLA
SCHEMBL10204584 0.83 MEN1 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL28353012 0.83 TP53 (0.53) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL4153728 0.83 ACHE (0.52) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL2593427 0.81 MEN1 (0.44) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL28177519 0.81 NPC1 (0.54) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL14465819 0.80 TAAR1 (0.50) ALDH1A1MEN1KMT2ATAAR1NPC1
SCHEMBL11951511 0.80 ALOX5 (0.50) ALDH1A1SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL4557778 0.80 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL286789 0.80 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-8084110-B2 Glycoluril resin and polyol resin members XEROX CORPORATION (US) 2011-12-27 US claimed
US-8067139-B2 Resin mixture backing layer containing photoconductor XEROX CORPORATION (US) 2011-11-29 US claimed
EP-2237114-A1 Glycoluril resin and polyol resin members Xerox Corporation (US) 2010-10-06 EP claimed
EP-2237115-A1 Intermediate transfer member comprising a coating of a mxiture of glycoluril resin and polyol resin Xerox Corporation (US) 2010-10-06 EP claimed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248103-A1 RESIN MIXTURE BACKING LAYER CONTAINING PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248107-A1 GLYCOLURIL RESIN AND POLYOL RESIN MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100221651-A1 EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US claimed
EP-2224288-A2 Epoxy carboxyl resin mixture hole blocking layer photoconductors Xerox Corporation (US) 2010-09-01 EP claimed
US-7579126-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2009-08-25 US claimed
US-20080220350-A1 Hole blocking layer containing photoconductors XEROX CORPORATION 2008-09-11 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
US-20020049290-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-25 US claimed
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 US claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed