Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 13/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914371 | 0.87 | PREP (0.46) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL8359911 | 0.82 | DPP4 (0.62) | DPP4DPP8DPP7DPP9FAP | |
| Hydrochloric Acid SCHEMBL4910106 | 0.81 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8360502 | 0.79 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13034909 | 0.79 | ITGB3 (0.47) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL4905274 | 0.78 | DPP4 (0.59) | PREPDPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4906566 | 0.78 | DPP4 (0.54) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL4905360 | 0.77 | DPP4 (0.53) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL4906172 | 0.77 | DPP4 (0.55) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL6111437 | 0.76 | PREP (0.48) | PREPDPP4DPP8DPP9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | FERRING B. V. | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | DPP4, DPP9, DPP3 | PREP 7/4885DPP4 1/4885DPP8 9/4885 |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | PREP 1/4885DPP4 3/4885DPP8 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.