Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25231629 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL195667 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL14966102 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL25336996 | 1.00 | TSHR (0.58) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL2413045 | 0.98 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL8386491 | 0.91 | TSHR (0.73) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL15923909 | 0.91 | TSHR (0.73) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL678273 | 0.91 | TSHR (0.73) | TSHRFAAHTRPV1HTTMEN1 | |
| SCHEMBL19040831 | 0.91 | TSHR (0.65) | TSHRFAAHTRPV1ALDH1A1HTT | |
| SCHEMBL10584770 | 0.91 | TSHR (0.73) | TSHRFAAHTRPV1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806503-B | Selective histone deacetylase inhibitor and preparation method and application thereof | 中国海洋大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-115806503-A | Selective histone deacetylase inhibitor as well as preparation method and application thereof | 中国海洋大学 | 2023-03-17 | — | — | CN | disclosed |
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | WAKAMOTO PHARMACEUTICAL CO., LTD (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1820799-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | GABRA5, GABRA1, GABRB1 | TSHR 1671/4885FAAH 3283/4885TRPV1 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.