SCHEMBL491229

SCHEMBL491229

COC(=O)N(C)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
NPC1 O15118 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
L3MBTL1 Q9Y468 5/20 0.54
NPSR1 Q6W5P4 2/20 0.53
CHRNB2 P17787 1/20 0.51
CHRNB4 P30926 1/20 0.51
CHRNA3 P32297 1/20 0.51
CHRNA4 P43681 1/20 0.51
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
LIPE Q05469 1/20 0.48
ALOX15 P16050 2/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2091346 0.84 LMNA (0.47) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL16667634 0.83 RAB9A (0.54) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL23064984 0.83 RAB9A (0.54) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL10033273 0.82 NPC1 (0.49) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL2093188 0.81 HSD17B2 (0.56) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL15161225 0.81 ALDH1A1 (0.51) RAB9ASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL1820109 0.81 RAB9A (0.53) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL8861880 0.81 CA12 (0.47) SMN1; SMN2MEN1KMT2AL3MBTL1NPSR1
SCHEMBL514386 0.81 SMN1; SMN2 (0.53) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL1838819 0.81 RAB9A (0.53) RAB9ASMN1; SMN2NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877365-A1 SUBSTITUTED TOLYL AS FUNGICIDES FMC CORPORATION (US) 2021-09-15 EP claimed
CN-110596273-A Method for rapidly identifying natural and artificial vitamin E in health product 浙江省疾病预防控制中心 2019-12-20 CN claimed
CN-108896694-B A kind of remaining LC-QToF-MS Screening analysis method of pesticide in animal food 中国农业科学院农业质量标准与检测技术研究所 2019-09-27 CN claimed
CN-110089328-A The method for eradicating Citrus Huanglongbing pathogen 郑建秋 2019-08-06 CN claimed
CN-105682461-B Pesticidal combination and relative method 美国陶氏益农公司 2019-06-14 CN claimed
CN-108896694-A A kind of remaining LC-QToF-MS Screening analysis method of pesticide in animal food 中国农业科学院农业质量标准与检测技术研究所 2018-11-27 CN claimed
CN-108282996-A Microbial compositions for use in combination with soil insecticides to promote plant growth FMC有限公司 2018-07-13 CN claimed
CN-104981154-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-01-26 CN claimed
CN-107183046-A A kind of Pesticidal combination of containing chlorine fluorine cyanogen insect amide 浙江省化工研究院有限公司 2017-09-22 CN claimed
CN-107156117-A A kind of modification infusorial earth base pesticide slow-release granule and preparation method 大连工业大学 2017-09-15 CN claimed
CN-101099467-A Pesticidal compositions SYNGENTA CROP PROT INC (CH) 2008-01-09 CN claimed
CN-101077072-A Pesticide composition NOVARTIS AG (CH) 2007-11-28 CN claimed
CN-1739351-A Pesticide composition NOVARTS AG (CH) 2006-03-01 CN claimed
CN-1401234-A Pesticide composition NOVARTIS AG (CH) 2003-03-12 CN claimed
CN-1386419-A Composite insecticide containing macrolide insect repellents for sanitary purpose WANG YUWAN (CN) 2002-12-25 CN claimed
CN-1297683-A pesticide composition of diesel oil and carbamate WANG HAIYU (CN) 2001-06-06 CN claimed
CN-1247709-A Spray pesticide for preventing and killing abdominal leg pests ZHAO XIAOWU (CN) 2000-03-22 CN claimed
CN-1168761-A Long-acting hygienic molecular microcapsule composition for chemicals and process for producing same LI JINLONG (CN) 1997-12-31 CN claimed
CN-1153594-A Floating liquid pesticide capable of spreading automatically on the surface of water UNIV HARBIN POLYTECHNIC (CN) 1997-07-09 CN claimed
CN-1093219-A Water soluble solid aerosol for hygiene purpose TAN GUIZHONG (CN) 1994-10-12 CN claimed