Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | CCR4 | P51679 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CCR5 | P51681 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008653 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL4909619 | 0.84 | CCR2 (1.00) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4910021 | 0.84 | CCR2 (0.87) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4903092 | 0.84 | CCR2 (0.80) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4911750 | 0.83 | CCR2 (0.78) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4907449 | 0.83 | CCR2 (0.75) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4912645 | 0.82 | CCR2 (1.00) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL14006426 | 0.82 | CCR2 (0.75) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4911238 | 0.82 | CCR2 (0.82) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4910156 | 0.82 | CCR2 (1.00) | CCR2CYP3A4CYP2C9CYP2C19CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | CCR2 1/4885CYP3A4 1414/4885CYP2C9 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.