SCHEMBL491378

SCHEMBL491378

C=CC(=O)N(C)Cc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.65
RAB9A P51151 3/20 0.65
CA12 O43570 2/20 0.59
CA9 Q16790 2/20 0.59
KMT2A Q03164 4/20 0.54
EGFR P00533 2/20 0.53
ITK Q08881 2/20 0.53
MEN1 O00255 2/20 0.53
HPGD P15428 2/20 0.51
RIPK1 Q13546 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 1/20 0.49
MGLL Q99685 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19472466 0.90 EGFR (0.50) NPC1RAB9ACA12CA9KMT2A
SCHEMBL19481325 0.84 EGFR (0.46) NPC1RAB9ACA12CA9KMT2A
SCHEMBL4889217 0.84 MTOR (0.50) NPC1RAB9ACA12CA9EGFR
SCHEMBL23227079 0.84 ALDH1A1 (0.54) NPC1RAB9ACA12CA9EGFR
SCHEMBL3163930 0.83 NPC1 (0.61) NPC1RAB9ACA12CA9KMT2A
SCHEMBL14562610 0.83 NPC1 (0.61) NPC1RAB9ACA12CA9KMT2A
SCHEMBL295841 0.82 LMNA (0.53) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL10796032 0.82 TAAR1 (0.50) NPC1RAB9AKMT2AMEN1
SCHEMBL16257002 0.82 BCL2A1 (0.56) NPC1RAB9AKMT2AEGFRITK
SCHEMBL3285709 0.82 NPC1 (0.47) NPC1RAB9ACA12CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850120-A Preparation method of alcohol alpha-carbon hydrogen bond alkylated compound 浙江工业大学 2023-03-28 CN claimed
CN-107615062-A Hydrogel particles with tunable optical properties and methods of using the same 弹弓生物科学公司 2018-01-19 CN claimed
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-8084110-B2 Glycoluril resin and polyol resin members XEROX CORPORATION (US) 2011-12-27 US claimed
US-8067139-B2 Resin mixture backing layer containing photoconductor XEROX CORPORATION (US) 2011-11-29 US claimed
EP-2237114-A1 Glycoluril resin and polyol resin members Xerox Corporation (US) 2010-10-06 EP claimed
EP-2237115-A1 Intermediate transfer member comprising a coating of a mxiture of glycoluril resin and polyol resin Xerox Corporation (US) 2010-10-06 EP claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
EP-0889916-B1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE UPJOHN CO (US) 2003-05-07 EP claimed
EP-0889916-A4 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE PHARMACIA IOVISION INC (US) 2000-06-28 EP claimed
EP-0889916-A1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE Pharmacia Iovision Inc. (US) 1999-01-13 EP claimed
WO-1998008787-A2 RESOLUTION OF RACEMIC MIXTURES USING POLYMERS CONTAINING CHIRAL UNITS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-05 WO claimed
US-5717049-A INTRAOCULAR LENSES PHARMACIA IOVISION, INC. (US) 1998-02-10 US claimed
WO-1997035896-A1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE PHARMACIA IOVISION INC. (US) 1997-10-02 WO claimed
US-4959360-A α-adrenergic receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1990-09-25 US claimed
EP-0356979-A2 Thermoplastic moulding composition based upon a mixture from a polycarbonate, a styrene-acrylonitrile copolymerisate and a shell-grafted rubber BASF Aktiengesellschaft (DE) 1990-03-07 EP claimed