SCHEMBL4914035

SCHEMBL4914035

CCCCCCCCCCCCC(Cc1ccccc1)[C](C)C

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.58
MMP2 P08253 17/20 0.50
MMP3 P08254 12/20 0.50
MMP1 P03956 10/20 0.50
MMP7 P09237 6/20 0.47
FOLH1 Q04609 1/20 0.46
CNR2 P34972 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667611 1.00 CSNK1E (0.58) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL4926240 1.00 CSNK1E (0.58) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL717704 1.00 CSNK1E (0.58) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL3400024 1.00 CSNK1E (0.58) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL2782163 1.00 CSNK1E (0.58) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL11624296 0.93 CSNK1E (0.49) CSNK1EMMP2MMP3MMP1FOLH1
SCHEMBL5017227 0.87 MMP2 (0.57) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL28211408 0.87 MMP2 (0.57) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL10801653 0.85 CSNK1E (0.56) CSNK1EMMP2MMP3MMP1MMP7
SCHEMBL10955140 0.85 FOLH1 (0.66) CSNK1EMMP2MMP3MMP1MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853605-B1 INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS BRACCO IMAGING SPA (IT) 2014-09-10 EP claimed
EP-0954518-A1 NEW POLYDYNAMIC CHEMICAL COMPOSITION OF MULTIPLE APPLICATIONS AND METHOD OF PREPARATION THEREOF Venetsianos, Timoleon (GR) 1999-11-10 EP claimed
WO-1998035933-A1 NEW POLYDYNAMIC CHEMICAL COMPOSITION OF MULTIPLE APPLICATIONS AND METHOD OF PREPARATION THEREOF VENETSIANOS TIMOLEON (GR) 1998-08-20 WO claimed
US-9334161-B2 Processing liquid for suppressing pattern collapse of fine metal structure and method for producing fine metal structure using same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-05-10 US disclosed
US-9320834-B2 Hardenable antimicrobial composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-04-26 US disclosed
US-20150165097-A1 HARDENABLE ANTIMICROBIAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2015-06-18 US disclosed
US-20120181249-A1 PROCESSING LIQUID FOR SUPPRESSING PATTERN COLLAPSE OF FINE METAL STRUCTURE AND METHOD FOR PRODUCING FINE METAL STRUCTURE USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-07-19 US disclosed
US-20080248511-A1 METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS PROMEGA CORPORATION 2008-10-09 US disclosed
US-7303876-B2 Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases APPLERA CORPORATION (US) 2007-12-04 US disclosed
US-7067500-B2 Betaines as adjuvants to susceptibility testing and antimicrobial therapy INTEGRATED RESEARCH TECHNOLOGY, LLC (US) 2006-06-27 US disclosed
US-20050009045-A1 Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases APPLERA CORPORATION 2005-01-13 US disclosed
US-6762027-B2 EXTRACTING PREFERENTIAL NUCLEOTIDE SEQUENCE FROM TISSUE; OBTAIN TISSUE SAMPLE, EXPOSE TO DISRUPTION MIXTURE, BIND NUCLEIC ACID TO SOLID PHASE, RECOVER NUCLEOTIDE SEQUENCES APPLERA CORPORATION 2004-07-13 US disclosed
EP-0762828-A4 METHOD AND REAGENT SYSTEM FOR THE IMPROVED DETERMINATION OF WHITE BLOOD CELL SUBPOPULATIONS CARVER EDWARD LAWRENCE JR (US) 2002-03-20 EP disclosed
US-5895765-A USING A STRIP OF A NEGATIVELY CHARGED MATRIX MATERIAL HAVING A ZONE CONTAINING MOBILE, LABELED BINDING PARTNER FOR THE ANALYTE AND A SEPARATE ZONE FOR CAPTURING THE LABELED BINDING PARTNER; POLYALKOXYLATED AMINE SURFACTANT BAYER CORPORATION (US) 1999-04-20 US disclosed
EP-0762828-A1 METHOD AND REAGENT SYSTEM FOR THE IMPROVED DETERMINATION OF WHITE BLOOD CELL SUBPOPULATIONS Carver, Edward Lawrence, Jr. (US) 1997-03-19 EP disclosed
WO-1995032622-A1 METHOD AND REAGENT SYSTEM FOR THE IMPROVED DETERMINATION OF WHITE BLOOD CELL SUBPOPULATIONS CDC TECHNOLOGIES INC (US) 1995-12-07 WO disclosed
US-5316951-A Method for the improved determination of white blood cell subpopulations DREW SCIENTIFIC HOLDINGS, INC. 1994-05-31 US disclosed
US-5316725-A Separation by particle size Carver, Jr., Edward Lawrence (US) 1994-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080248511-A1 METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS GLO1, ESD, GLB1 CSNK1E 1680/4885MMP2 1338/4885MMP3 939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.