Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921990 | 0.90 | — | — | |
| SCHEMBL4721668 | 0.69 | CYP1A2 (0.49) | LTA4HCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL6694166 | 0.64 | — | — | |
| SCHEMBL10356302 | 0.63 | CYP2D6 (0.55) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| SCHEMBL30605677 | 0.62 | LTA4H (0.46) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| SCHEMBL10692851 | 0.62 | LTA4H (0.46) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| SCHEMBL18612818 | 0.61 | CYP2D6 (0.44) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| SCHEMBL26850 | 0.60 | LTA4H (0.70) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| Squaric Acid Dibutyl Ester SCHEMBL56180 | 0.60 | CYP3A4 (0.44) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 | |
| SCHEMBL13412631 | 0.58 | CYP1A2 (0.52) | LTA4HCYP1A2CYP2C9CYP2C19NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200475-A1 | 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors | PFIZER INC. | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200475-A1 | 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors | PF4, TBXA2R, P2RY4 | LTA4H 496/4885CYP1A2 578/4885CYP2C9 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.