SCHEMBL491425

SCHEMBL491425

[CH](C1CCCC1)C1CCCC1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524657 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL984941 0.96
SCHEMBL1173999 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL6101790 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL10494046 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11001515 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL22033837 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL22033682 0.96 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3883393 0.92 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9004375 0.92 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220024926-A1 A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-01-27 US claimed
CN-113717170-A Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2021-11-30 CN claimed
CN-112745316-A Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2021-05-04 CN claimed
CN-112679495-A Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2021-04-20 CN claimed
WO-2020118139-A1 A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-06-11 WO claimed
US-20080171662-A1 Aminocarbonyl-Substituted Thiensulfonylamino(Thio)Carbonyl-Triazolin(Ethi)Ones, Processes For Their Preparation And Their Use BAYER CROPSCIENCE AG (DE) 2008-07-17 US claimed
WO-2007118474-A2 METHOD FOR THE PRODUCTION OF HYDROGEN-RICH SILANES, AND NOVEL CHEMICAL COMPOUNDS TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) 2007-10-25 WO claimed
EP-1776012-A1 AMINOCARBONYL-SUBSTITUTED THIENSULPHONYLAMINO (THIO) CARBONYLTRIAZOLIN (THI) ONES METHODS FOR PRODUCTION AND USE THEREOF Bayer CropScience Aktiengesellschaft (DE) 2007-04-25 EP claimed
WO-2006012981-A1 AMINOCARBONYL-SUBSTITUTED THIENYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2006-02-09 WO claimed
WO-2006012983-A1 AMINOCARBONYL-SUBSTITUTED THIENSULPHONYLAMINO (THIO) CARBONYLTRIAZOLIN (THI) ONES METHODS FOR PRODUCTION AND USE THEREOF BAYER CROPSCIENCE AG (DE) 2006-02-09 WO claimed
EP-1623987-A1 Fused pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and pyrido[3',2':4,5]furo[3,2-d]pyrimidines Curacyte Discovery GmbH (DE) 2006-02-08 EP claimed
EP-1619196-A1 Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidines and Pyrido[3',2':4,5]furo[3,2-d]-pyrimidines for use as inhibitors of PDA-4 and/or TNF-alpha release Curacyte Discovery GmbH (DE) 2006-01-25 EP claimed
EP-1619197-A1 Substituted Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-2,4(1H,3H)diones and -4(3H)ones as well as Pyrido[3',2':4,5]furo[3,2-d]-pyrimidin-2,4(1H,3H)diones und -4(3H)ones as inhibitors of TNF-alpha release Curacyte Discovery GmbH (DE) 2006-01-25 EP claimed
EP-1104422-A1 PHENYL XANTHINE DERIVATIVES GLAXO GROUP LIMITED (GB) 2001-06-06 EP claimed
WO-2000009507-A1 PHENYL YANTHINE DERIVATIVES GLAXO GROUP LIMITED (GB) 2000-02-24 WO claimed
US-20230242785-A1 PHOTOCURABLE COMPOSITION, THREE-DIMENSIONAL MODELING PRODUCT, AND DENTAL PRODUCT MITSUI CHEMICALS, INC. (JP) 2023-08-03 US disclosed
EP-4163308-A1 PHOTOCURABLE COMPOSITION, THREE-DIMENSIONAL SHAPED ARTICLE, AND DENTAL PRODUCT Mitsui Chemicals, Inc. (JP) 2023-04-12 EP disclosed
US-5217856-A TETRAAZAPORPHIN, PROCESS FOR PRODUCING THE SAME, AS WELL AS OPTICAL RECORDING MEDIA USING THE SAME AND PRODUCTION PROCESSES THEREOF HITACHI CHEMICAL CO., LTD. (JP) 1993-06-08 US disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed
EP-0344891-A2 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1989-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171662-A1 Aminocarbonyl-Substituted Thiensulfonylamino(Thio)Carbonyl-Triazolin(Ethi)Ones, Processes For Their Preparation And Their Use TST, SULT1E1, CBR3 ALDH1A1 996/4885THRB 230/4885MEN1 3811/4885
US-20220024926-A1 A1 ADENOSINE RECEPTOR AGONISTS AND METHODS OF USE THEREOF ADORA1, ADORA2A, ADORA2B ALDH1A1 231/4885THRB 144/4885MEN1 1679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.