Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925378 | 0.92 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL4923477 | 0.88 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4926872 | 0.85 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL3090775 | 0.77 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL3080372 | 0.77 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL3068214 | 0.77 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL5388303 | 0.72 | CNR2 (0.67) | CNR1CNR2 | |
| SCHEMBL14144372 | 0.72 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL11594212 | 0.72 | ENPP2 (0.36) | CNR1CNR2 | |
| SCHEMBL3078940 | 0.72 | CNR1 (0.63) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, GPR35 | CNR1 1/4885CNR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.