Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.51 |
| ▸ | CNR2 | P34972 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923477 | 0.92 | CNR1 (0.48) | CNR1CNR2KCNH2ABCC4MLNR | |
| SCHEMBL4914683 | 0.92 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL4926872 | 0.89 | CNR1 (0.56) | CNR1CNR2KCNH2ABCC4MLNR | |
| SCHEMBL8132350 | 0.78 | PTGS2 (0.59) | HTR2AHTR2B | |
| SCHEMBL5338137 | 0.77 | CNR1 (0.51) | CNR1CNR2KCNH2OPRL1 | |
| SCHEMBL695378 | 0.76 | SRC (0.46) | CNR1HTR2AHTR2B | |
| SCHEMBL28691202 | 0.75 | PTGS2 (0.59) | CNR1HTR2AHTR2B | |
| SCHEMBL3081746 | 0.74 | CNR1 (0.52) | CNR1CNR2KCNH2ABCC4MLNR | |
| SCHEMBL3068288 | 0.74 | CNR1 (0.52) | CNR1CNR2KCNH2ABCC4MLNR | |
| SCHEMBL3083146 | 0.74 | CNR1 (0.52) | CNR1CNR2KCNH2ABCC4MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, GPR35 | CNR1 1/4885CNR2 2/4885KCNH2 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.