SCHEMBL4915096

SCHEMBL4915096

NC[C@H](NCc1ccc(OCc2ccccc2)cc1)C(=O)NO

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.51
LTA4H P09960 2/20 0.51
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4915087 1.00 BCHE (0.51) BCHELTA4HMMP9MMP8
SCHEMBL404744 0.83 MEP1B (0.49) MMP9
SCHEMBL4534760 0.81 FFAR1 (0.45)
SCHEMBL1070410 0.80 BCHE (0.54) BCHE
SCHEMBL7394895 0.80 BCHE (0.54) BCHE
SCHEMBL7396992 0.80 BCHE (0.54) BCHE
SCHEMBL6034466 0.79 PPARG (0.62) BCHEMMP9MMP8
SCHEMBL8413776 0.79 PPARG (0.62) BCHEMMP9MMP8
SCHEMBL6034470 0.79 PPARG (0.62) BCHEMMP9MMP8
SCHEMBL1855602 0.79 PPARG (0.62) BCHEMMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 BCHE 1049/4885LTA4H 2801/4885MMP9 856/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 BCHE 1220/4885LTA4H 2998/4885MMP9 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.