SCHEMBL4916420

SCHEMBL4916420

Cc1ccc(O)c(NC(=O)c2ccccc2-c2ccccc2C(=O)NO)c1

nearest known ligand 0.80

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.80
KCNMA1 Q12791 9/20 0.65
RAB9A P51151 2/20 0.58
LMNA P02545 1/20 0.58
TSHR P16473 1/20 0.58
HSD17B10 Q99714 1/20 0.58
HDAC7 Q8WUI4 1/20 0.54
TP53 P04637 2/20 0.53
NPC1 O15118 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
MEN1 O00255 3/20 0.52
HCRTR1 O43613 1/20 0.52
KDM4E B2RXH2 1/20 0.49
HIF1A Q16665 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4928655 0.93 KCNMA1 (0.70) GAAKCNMA1RAB9ALMNATSHR
SCHEMBL4923998 0.85 KCNMA1 (0.60) GAAKCNMA1RAB9ALMNATSHR
SCHEMBL4927648 0.82 GAA (0.69) GAAKCNMA1RAB9ALMNATSHR
SCHEMBL14363390 0.82 KCNMA1 (0.66) GAAKCNMA1RAB9ALMNATSHR
SCHEMBL4925929 0.80 GAA (0.52) GAAKCNMA1RAB9ALMNATP53
SCHEMBL10873010 0.76 KCNMA1 (1.00) GAAKCNMA1RAB9ATSHRTP53
SCHEMBL4923931 0.76 HSD17B10 (0.54) GAAKCNMA1RAB9ALMNATSHR
SCHEMBL1759402 0.75 CSNK2A1 (0.64) GAARAB9ALMNAHDAC7SMN1; SMN2
SCHEMBL12636131 0.75 CSNK2A1 (0.64) GAARAB9ALMNAHDAC7SMN1; SMN2
SCHEMBL3026631 0.74 GAA (0.64) GAALMNAHSD17B10HDAC7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 GAA 1690/4885KCNMA1 1918/4885RAB9A 4301/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 GAA 1635/4885KCNMA1 1781/4885RAB9A 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.