SCHEMBL4916799

SCHEMBL4916799

O=C(Cc1ccccc1C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.53
MAPT P10636 3/20 0.50
GAA P10253 1/20 0.50
CYP19A1 P11511 1/20 0.49
SRD5A2 P31213 1/20 0.49
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CES1 P23141 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2C9 P11712 1/20 0.46
GSK3B P49841 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338530 0.86 FOLH1 (0.53) AKR1C3MAPTSRD5A2MAPK1TDP1
SCHEMBL56318 0.86 BCAT2 (0.56) AKR1C3MAPTGAACYP19A1TDP1
SCHEMBL11036287 0.84 AKR1C3 (0.61) AKR1C3MAPTGAACYP19A1SRD5A2
SCHEMBL7196858 0.83 MAPT (0.61) MAPTGAASRD5A2MAPK1TDP1
SCHEMBL4725086 0.83 KMT2A (0.47) MAPTMAPK1TDP1KDM4EMEN1
SCHEMBL9565671 0.83 CES1 (0.52) MAPTMAPK1TDP1KDM4EMEN1
SCHEMBL1569111 0.83 MAPT (0.53) AKR1C3MAPTGAACYP19A1TDP1
SCHEMBL14976814 0.83 MAPT (0.48) MAPTMAPK1TDP1KDM4EMEN1
SCHEMBL9277399 0.83 AKR1C3 (0.52) AKR1C3MAPTGAACYP19A1TDP1
SCHEMBL1122035 0.83 AKR1C3 (0.52) AKR1C3MAPTGAACYP19A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106980230-B Photosensitive resin composition, color filter using the same, and display device 东京应化工业株式会社 2020-05-19 CN disclosed
US-8871831-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2014-10-28 US disclosed
US-20140058032-A1 MODIFICATION OF SURFACES WITH POLYMERS CARNEGIE MELLON UNIVERSITY 2014-02-27 US disclosed
US-20130131278-A1 MODIFICATION OF SURFACES WITH POLYMERS NATIONAL SCIENCE FOUNDATION 2013-05-23 US disclosed
US-8349410-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2013-01-08 US disclosed
US-20080139689-A1 Controlled free radical polymerization, crosslinking, Norrish reaction; segments can be hydrophilicity, hydrophobicity, biocompatibility, bioactivity, adhesion, adsorption; corrosion, abrasion and, heat resistance; dielectrics; poly(3-(trimethoxysilyl)propyl methacrylate) segment; quaternized groups NATIONAL SCIENCE FOUNDATION 2008-06-12 US disclosed
US-20060154098-A1 Self-adhesive article TESA AG (DE) 2006-07-13 US disclosed