SCHEMBL56318

SCHEMBL56318

O=C(O)Cc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.56
ABCB11 O95342 1/20 0.55
LMNA P02545 1/20 0.55
PTGS1 P23219 1/20 0.55
ADORA1 P30542 1/20 0.55
PTGS2 P35354 1/20 0.55
AKR1B1 P15121 2/20 0.55
AKR1C3 P42330 1/20 0.55
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
ALDH1A1 P00352 2/20 0.50
CYP19A1 P11511 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP2C8 P10632 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11147593 0.89 SRD5A2 (0.57) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL22776859 0.88 ABCB11 (0.52) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL2122049 0.88 ABCB11 (0.73) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL30965933 0.88 ABCB11 (0.52) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL4916799 0.86 AKR1C3 (0.53) LMNAAKR1C3GAAMAPTALDH1A1
Hydrochloric Acid SCHEMBL11544674 0.86 NR4A1 (0.60) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL11036287 0.85 AKR1C3 (0.61) AKR1C3GAAMAPTALDH1A1CYP19A1
SCHEMBL8267499 0.85 LMNA (0.50) BCAT2ABCB11LMNAPTGS1ADORA1
SCHEMBL1569111 0.85 MAPT (0.53) ABCB11LMNAPTGS1ADORA1PTGS2
SCHEMBL9277399 0.85 AKR1C3 (0.52) BCAT2ABCB11LMNAPTGS1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326915-B1 A LOCALLY ADMINISTRABLE THERAPEUTIC COMPOSITION FOR INFLAMMATORY DISEASE Senju Pharmaceutical Co., Ltd. (JP) 1992-09-02 EP claimed
US-4910225-A Benzoylphenylacetic acid SENJU PHARMACEUTICAL CO., LTD. (JP) 1990-03-20 US claimed
EP-0231375-B1 PHOTO-SETTING COMPOSITION SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-01-24 EP claimed
EP-0326915-A1 A locally administrable therapeutic composition for inflammatory disease Senju Pharmaceutical Co., Ltd. (JP) 1989-08-09 EP claimed
EP-0231375-A1 PHOTO-SETTING COMPOSITION SHOWA DENKO KABUSHIKI KAISHA (JP) 1987-08-12 EP claimed
US-3962303-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-06-08 US claimed
US-3931286-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-01-06 US claimed
JP-2124817-A None JP disclosed
WO-2025038899-A2 METHODS FOR CARBON DIOXIDE SEPARATION AND MATERIALS AND SYSTEMS FOR SAME CORNELL UNIVERSITY (US) 2025-02-20 WO disclosed
US-20200360326-A1 Aqueous Liquid Composition Containing 2-Amino-3-(4-Bromobenzoyl)Phenylacetic Acid BAUSCH & LOMB INCORPORATED 2020-11-19 US disclosed
US-10646435-B2 Pasty bio-adhesive sustained release compositions CARE & PHARMA PERSPECTIVES SA (CH) 2020-05-12 US disclosed
WO-2020059485-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIN SHEET, CURED FILM, ORGANIC EL DISPLAY DEVICE, SEMICONDUCTOR ELECTRONIC COMPONENT, SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING ORGANIC EL DISPLAY DEVICE 東レ株式会社 2020-03-26 WO disclosed
US-9914697-B2 Methods for making polymorphs of bromfenac sodium and bromfenac sodium formulations JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2018-03-13 US disclosed
US-3975531-A ANTIINFLAMMATORY A. H. ROBINS COMPANY, INCORPORATED (US) 1976-08-17 US disclosed
US-3962303-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-06-08 US disclosed
US-3962303-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-06-08 US disclosed
US-3962303-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-06-08 US disclosed
US-3931286-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed
US-3931286-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed
US-3931286-A Novel benzoylphenylacetic acid derivatives ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360326-A1 Aqueous Liquid Composition Containing 2-Amino-3-(4-Bromobenzoyl)Phenylacetic Acid AADAT, UACA, IL4 BCAT2 36/4885ABCB11 963/4885LMNA 1636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.