Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | CES2 | O00748 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338530 | 0.85 | FOLH1 (0.53) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL1579502 | 0.84 | CES2 (0.50) | CES1CES2MAPTALDH1A1LMNA | |
| SCHEMBL4916799 | 0.83 | AKR1C3 (0.53) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL7196858 | 0.82 | MAPT (0.61) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL14976814 | 0.81 | MAPT (0.48) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL4725086 | 0.81 | KMT2A (0.47) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL5704111 | 0.81 | CES2 (0.56) | CES1CES2MAPTALDH1A1RAB9A | |
| SCHEMBL8393132 | 0.81 | CES2 (0.47) | CES1CES2MAPK1MAPTHPGD | |
| SCHEMBL10780174 | 0.80 | LMNA (0.50) | CES1MAPK1MAPTTDP1KDM4E | |
| SCHEMBL27905657 | 0.80 | CES2 (0.50) | CES1CES2MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556818-A1 | Polyester type polyfunctional macromonomer, gel and drug release controlling material responsive to changes in temperature | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-08-25 | — | — | EP | disclosed |