Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.57 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920409 | 0.81 | OPRM1 (0.45) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| SCHEMBL7094966 | 0.80 | OPRM1 (0.51) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| SCHEMBL6593964 | 0.80 | KCNH2 (0.52) | OPRM1OPRD1OGFRL1OPRK1KCNH2 | |
| SCHEMBL4915316 | 0.79 | HDAC3 (0.55) | OGFRL1HDAC3HDAC1HDAC10HDAC6 | |
| SCHEMBL6992893 | 0.77 | KCNH2 (0.59) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| SCHEMBL7094995 | 0.76 | OPRM1 (0.46) | OPRM1OPRD1OGFRL1OPRK1KCNH2 | |
| SCHEMBL4910158 | 0.76 | CYP1A2 (0.50) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| SCHEMBL4918658 | 0.76 | NR4A2 (0.45) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| Hydrochloric Acid SCHEMBL5009615 | 0.76 | KCNH2 (0.58) | OPRM1OPRD1OGFRL1OPRK1NR4A2 | |
| SCHEMBL4910139 | 0.75 | NR4A2 (0.44) | OPRM1OPRD1OGFRL1OPRK1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | ICAGEN, INC. (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | TRPV3, SCN3A, TRPV1 | OPRM1 339/4885OPRD1 267/4885OGFRL1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.