Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922086 | 0.85 | SIRT6 (0.59) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13991135 | 0.81 | MEN1 (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4918800 | 0.81 | MAPT (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4916267 | 0.80 | KMT2A (0.48) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13991068 | 0.80 | KMT2A (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4915691 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13991071 | 0.79 | MEN1 (0.41) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13991136 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17422247 | 0.78 | MAPT (0.55) | ALDH1A1MAPTMEN1KMT2AGPR174 | |
| SCHEMBL13991066 | 0.77 | CYP2C9 (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080317806-A1 | Antiparasitic Compounds | MURDOCH UNIVERSITY (AU) | 2008-12-25 | — | — | US | disclosed |
| EP-1871743-A1 | ANTIPARASITIC COMPOUNDS | Murdoch University (AU) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108224-A1 | ANTIPARASITIC COMPOUNDS | MURDOCH UNIVERSITY (AU) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080317806-A1 | Antiparasitic Compounds | CYCS, CBR3, CBR1 | ALDH1A1 2244/4885MAPT 4817/4885MEN1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.