Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919762 | 0.81 | SIRT2 (0.40) | SIRT1SIRT2GRM5IDO1ELANE | |
| SCHEMBL4919786 | 0.76 | GAA (0.36) | SIRT1SIRT2HCRTR1HCRTR2KDM4E | |
| SCHEMBL4914804 | 0.68 | ELANE (0.63) | SIRT1SIRT2ELANECTSGPRTN3 | |
| SCHEMBL4923566 | 0.65 | SIRT2 (0.40) | SIRT1SIRT2 | |
| SCHEMBL4918740 | 0.64 | SIRT2 (0.36) | SIRT1SIRT2GRM5ELANECTSG | |
| SCHEMBL4910875 | 0.61 | SIRT2 (0.39) | SIRT1SIRT2HCRTR1HCRTR2KDM4E | |
| SCHEMBL10751909 | 0.61 | BRD4 (0.43) | SIRT1SIRT2ELANECTSGPRTN3 | |
| SCHEMBL4030757 | 0.60 | FDPS (0.43) | KDM4EALDH1A1HPGDRCE1FDPS | |
| SCHEMBL4919164 | 0.60 | MAPK1 (0.39) | SIRT1SIRT2KDM4EALDH1A1HPGD | |
| SCHEMBL513344 | 0.59 | SIRT2 (0.40) | SIRT1SIRT2ALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | NIHON NOHYAKU CO., LTD. (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1852425-A1 | NOVEL HALOALKYLSULFONANILIDE DERIVATIVE, HERBICIDE, AND METHOD OF USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | HDHD5, DDT, CBR3 | SIRT1 1312/4885SIRT2 1134/4885GRM5 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.