SCHEMBL4914804

SCHEMBL4914804

CC1(C)OC(=O)N(Cc2ccccc2N)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.63
PRTN3 P24158 2/20 0.63
CTSG P08311 1/20 0.63
CLTC Q00610 1/20 0.37
LMNA P02545 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
FDPS P14324 1/20 0.36
GRM2 Q14416 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
PGR P06401 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
NR3C2 P08235 1/20 0.33
CTSK P43235 1/20 0.33
TACR1 P25103 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4909147 0.77 ELANE (0.57) ELANEPRTN3CTSGLMNASIRT2
SCHEMBL4919328 0.72 ELANE (0.50) ELANEPRTN3CTSGPTGS1PTGS2
SCHEMBL5257643 0.70 ELANE (0.73) ELANEPRTN3CTSGLMNAGRM2
SCHEMBL8320094 0.70 ELANE (0.73) ELANEPRTN3CTSGLMNAGRM2
SCHEMBL4919762 0.70 SIRT2 (0.40) ELANEPRTN3CTSGLMNASIRT2
SCHEMBL10751909 0.69 BRD4 (0.43) ELANEPRTN3CTSGCLTCSIRT2
SCHEMBL4918740 0.69 SIRT2 (0.36) ELANEPRTN3CTSGSIRT2SIRT1
SCHEMBL11413584 0.68 CLTC (0.54) CLTCALDH1A1TSHR
SCHEMBL4917459 0.68 SIRT1 (0.38) ELANEPRTN3CTSGSIRT2SIRT1
Ethadione SCHEMBL35279 0.67 ELANE (0.55) ELANEPRTN3CTSGLMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274892-A1 Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof NIHON NOHYAKU CO., LTD. (JP) 2008-11-06 US disclosed
EP-1852425-A1 NOVEL HALOALKYLSULFONANILIDE DERIVATIVE, HERBICIDE, AND METHOD OF USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2007-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274892-A1 Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof HDHD5, DDT, CBR3 ELANE 4416/4885PRTN3 3689/4885CTSG 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.