Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16693057 | 0.81 | CYP2A6 (0.58) | CYP2A6FLT3LOXL2APPPOLB | |
| SCHEMBL533466 | 0.81 | CYP2A6 (0.58) | CYP2A6FLT3LOXL2APPPOLB | |
| SCHEMBL3979881 | 0.74 | CYP2A6 (0.50) | CYP2A6APPSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3979876 | 0.74 | CYP2A6 (0.50) | CYP2A6APPSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17185672 | 0.74 | CYP2A6 (0.64) | CYP2A6CA2FLT3LOXL2APP | |
| SCHEMBL11396362 | 0.74 | CYP2A6 (0.64) | CYP2A6CA2FLT3LOXL2APP | |
| SCHEMBL2900756 | 0.74 | CYP2A6 (0.64) | CYP2A6CA2FLT3LOXL2APP | |
| SCHEMBL9956377 | 0.74 | CYP2A6 (1.00) | CYP2A6CA2FLT3LOXL2APP | |
| SCHEMBL91009 | 0.74 | CYP2A6 (1.00) | CYP2A6CA2FLT3LOXL2APP | |
| SCHEMBL1706926 | 0.74 | CYP2A6 (0.64) | CYP2A6CA2FLT3LOXL2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |
| US-20080064730-A1 | Azine Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| EP-1827102-A1 | AZINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006056462-A9 | AZINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2006056462-A1 | AZINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | WO | disclosed |
| EP-1631143-A1 | HYDRAZONE DERIVATIVES FOR COMBATTING HARMFUL INSECTS AND ARACHNIDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004105488-A1 | HYDRAZONE DERIVATIVES FOR COMBATTING HARMFUL INSECTS AND ARACHNIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-09 | — | — | WO | disclosed |
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | disclosed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064730-A1 | Azine Compounds for Combating Animal Pests | PARK7, OR10J3, TAS2R7 | CYP2A6 1409/4885CA2 2648/4885FLT3 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.