Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4917369 | 0.76 | ACHE (0.45) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL4919438 | 0.74 | ACHE (0.51) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL1963821 | 0.73 | ACHE (0.48) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL1963337 | 0.72 | ACHE (0.53) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL2783969 | 0.71 | ALDH1A1 (0.53) | ACHECA12CA9ALDH1A1TSHR | |
| SCHEMBL4923632 | 0.71 | ACHE (0.48) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL4918818 | 0.71 | ACHE (0.45) | ACHECA12CA9ALDH1A1TSHR | |
| SCHEMBL1963519 | 0.71 | ACHE (0.48) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL1964986 | 0.70 | ACHE (0.47) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL4919773 | 0.69 | SIRT2 (0.52) | ACHESIRT2SIRT1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | NIHON NOHYAKU CO., LTD. (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1852425-A1 | NOVEL HALOALKYLSULFONANILIDE DERIVATIVE, HERBICIDE, AND METHOD OF USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | HDHD5, DDT, CBR3 | ACHE 357/4885SIRT2 1134/4885SIRT1 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.