SCHEMBL4919231

SCHEMBL4919231

NC(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
LMNA P02545 3/20 0.59
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
ALDH1A1 P00352 3/20 0.48
CYP3A4 P08684 2/20 0.48
TSHR P16473 2/20 0.46
POLB P06746 1/20 0.46
PARP1 P09874 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MDM2 Q00987 1/20 0.45
CYP2D6 P10635 1/20 0.44
SRC P12931 1/20 0.44
DPP4 P27487 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3658372 1.00 TDP1 (0.61) TDP1L3MBTL1LMNACES2CES1
Hydrochloric Acid SCHEMBL9150834 0.98 TDP1 (0.59) TDP1L3MBTL1LMNACES2CES1
Chlorobenzene SCHEMBL27608976 0.90 TDP1 (0.52) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11205532 0.89 TDP1 (0.54) TDP1L3MBTL1LMNACES2CES1
SCHEMBL8805626 0.86 NPC1 (0.50) TDP1L3MBTL1LMNACES2CES1
SCHEMBL6205111 0.86 CES2 (0.52) TDP1L3MBTL1LMNACES2CES1
Hydrochloric Acid SCHEMBL4015538 0.85 CES2 (0.50) TDP1L3MBTL1LMNACES2CES1
Hydrochloric Acid SCHEMBL4329394 0.85 NPC1 (0.49) TDP1L3MBTL1LMNACES2CES1
SCHEMBL3320904 0.82 MEN1 (0.54) TDP1L3MBTL1LMNACES2CES1
SCHEMBL6203223 0.82 ALDH1A1 (0.55) TDP1LMNAALDH1A1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003699-B Protective printing ink for glass acid etching process and preparation method and application thereof 广州亦盛环保科技有限公司 2021-08-06 CN claimed
CN-115926534-A UV curable inkjet ink composition 韩国太阳油墨股份公司 2023-04-07 CN disclosed
CN-114787293-B Surface protective agent composition and covered electric wire with terminal 株式会社自动网络技术研究所 2023-04-04 CN disclosed
CN-112940560-B Photosensitive solder resist ink composition, use thereof and circuit board containing same 深圳市容大感光科技股份有限公司 2022-11-29 CN disclosed
CN-115298614-A Photosensitive material, transfer film, method for manufacturing circuit wiring, method for manufacturing touch panel, and pattern forming method 富士胶片株式会社 2022-11-04 CN disclosed
CN-115280239-A Transfer film, photosensitive material, pattern forming method, method for manufacturing circuit board, and method for manufacturing touch panel 富士胶片株式会社 2022-11-01 CN disclosed
CN-115197596-A High-flatness hardened film for carrier plate and preparation method thereof 广东硕成科技股份有限公司 2022-10-18 CN disclosed
CN-114787293-A Surface protective agent composition and covered electric wire with terminal 株式会社自动网络技术研究所 2022-07-22 CN disclosed
CN-109721566-B Preparation method of 1- (4-morpholine phenyl) -1-butanone 天津久日新材料股份有限公司 2022-03-22 CN disclosed
US-11129790-B2 Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates NORTHEASTERN UNIVERSITY (US) 2021-09-28 US disclosed
EP-0005156-B1 4,5-DIARYL-2-(SUBSTITUTED-THIO)-PYRROLES AND THEIR CORRESPONDING SULFOXIDES AND SULFONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-22 EP disclosed
US-4335136-A Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-15 US disclosed
EP-0038997-A1 Anti-inflammatory 4,5-diaryl-alpha, alpha-bis(polyfluoroalkyl)-1H-pyrrole-2-methane thiols, processes for their preparation and pharmaceutical compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-04 EP disclosed
EP-0038536-A1 Antiinflammatory 4,5-diaryl-alpha-(polyfluoroalkyl)-1H-pyrrole-2-methanamines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-28 EP disclosed
EP-0034798-A2 Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-02 EP disclosed
US-4267190-A AND METHOD OF ADMINISTERING TO MAMMALS FOR TREATMENT OF ARTHRITIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-12 US disclosed
US-4267184-A USEFUL FOR TREATING ARTHRITIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-12 US disclosed
EP-0025884-A1 4,5-Diaryl-alpha-polyfluoroalkyl-1H-pyrrole-2-methanols and 1-(4,5-diaryl-1H-pyrrol-2-yl)-polyfluoroalkanones, processes for preparing them and pharmaceutical compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-01 EP disclosed
EP-0005156-A1 4,5-diaryl-2-(substituted-thio)-pyrroles and their corresponding sulfoxides and sulfones, process for their preparation and pharmaceutical compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-11-14 EP disclosed
US-4020082-A ANTIPHLOGISTIC, ANALGESIC, ANTIAGGREGANT, LOCAL ANESTHETIC MARCHETTI ENZO 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11129790-B2 Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates GLUL, QPCT, DNPEP TDP1 1599/4885L3MBTL1 2682/4885LMNA 4624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.