Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.79 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916863 | 0.83 | HDAC6 (0.76) | HDAC6HDAC8HDAC3ALDH1A1HPGD | |
| SCHEMBL4920512 | 0.83 | HDAC6 (0.72) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL4919256 | 0.83 | HDAC6 (0.76) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL23052525 | 0.81 | CA12 (0.63) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL4927135 | 0.78 | HDAC6 (0.68) | HDAC6HDAC8HDAC3OPRK1HDAC11 | |
| SCHEMBL4930709 | 0.78 | MMP1 (0.68) | — | |
| SCHEMBL12078791 | 0.76 | HDAC3 (0.78) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL4923521 | 0.73 | POLB (0.72) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL13701763 | 0.73 | HDAC3 (0.61) | HDAC6HDAC8HDAC3OPRK1ALDH1A1 | |
| SCHEMBL21628465 | 0.73 | NPC1 (0.58) | HDAC6HDAC8HDAC3HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | HDAC6 2092/4885HDAC8 3399/4885HDAC3 3274/4885 |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | HDAC6 2060/4885HDAC8 3570/4885HDAC3 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.