Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21271432 | 0.77 | TSHR (0.44) | KMT2ARECQLPOLBMEN1 | |
| SCHEMBL21271433 | 0.77 | TSHR (0.44) | KMT2ARECQLPOLBMEN1 | |
| SCHEMBL21271435 | 0.77 | TSHR (0.44) | KMT2ARECQLPOLBMEN1 | |
| SCHEMBL4915631 | 0.77 | POLB (0.38) | KMT2APOLBCNR2HDAC1HDAC6 | |
| SCHEMBL21788017 | 0.72 | DNM1 (0.48) | KMT2ACNR1CNR2MEN1HDAC1 | |
| SCHEMBL19499067 | 0.70 | NOD1 (0.59) | KMT2APOLBMEN1 | |
| SCHEMBL16086393 | 0.69 | POLB (0.49) | KMT2APOLBHDAC1HDAC6 | |
| SCHEMBL17256371 | 0.69 | KMT2A (0.65) | KMT2APOLBMEN1 | |
| SCHEMBL8733276 | 0.69 | NOD1 (0.62) | KMT2APOLBMEN1 | |
| SCHEMBL8576701 | 0.69 | NOD1 (0.62) | KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |