Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CERT1 | Q9Y5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915642 | 0.81 | GAA (0.41) | KIF11GAAALDH1A1KMT2AHDAC1 | |
| SCHEMBL7615687 | 0.80 | KIF11 (0.45) | KIF11GAAALDH1A1KMT2ACNR2 | |
| SCHEMBL4920307 | 0.77 | KMT2A (0.43) | POLBKMT2AHDAC1HDAC6CNR2 | |
| SCHEMBL6516358 | 0.77 | HDAC1 (0.46) | GAAALDH1A1KMT2AHDAC1HDAC6 | |
| SCHEMBL7616339 | 0.74 | MEN1 (0.44) | KIF11GAAALDH1A1KMT2A | |
| SCHEMBL14946793 | 0.71 | KIF11 (0.41) | KIF11ALDH1A1HDAC1 | |
| SCHEMBL25631518 | 0.70 | KMT2A (0.45) | KMT2A | |
| SCHEMBL20371135 | 0.70 | HDAC6 (0.43) | GAAALDH1A1KMT2AHDAC6 | |
| SCHEMBL13032794 | 0.69 | HDAC6 (0.47) | HDAC1HDAC6 | |
| SCHEMBL24383374 | 0.69 | KMT2A (0.43) | ALDH1A1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |