Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224238 | 0.93 | PTGES (0.45) | PTGESGFERGALR3GAATP53 | |
| SCHEMBL4922786 | 0.88 | PTGES (0.62) | PTGESGFERGALR3GAATHRB | |
| SCHEMBL2997482 | 0.87 | PTGES (0.50) | PTGESGAATHRBSMN1; SMN2TP53 | |
| SCHEMBL3009731 | 0.87 | PTGES (0.52) | PTGESSMN1; SMN2TP53MAPTPOLB | |
| SCHEMBL3001458 | 0.86 | PTGES (0.51) | PTGESTHRBSMN1; SMN2TP53MAPT | |
| SCHEMBL3575712 | 0.86 | PTGES (0.64) | PTGESTHRBSMN1; SMN2TP53MAPT | |
| SCHEMBL4918706 | 0.86 | PTGES (0.64) | PTGESGFERGALR3GAASMN1; SMN2 | |
| SCHEMBL5265086 | 0.86 | NOD2 (0.49) | PTGESGAATHRBSMN1; SMN2TP53 | |
| SCHEMBL4924224 | 0.86 | PLA2G10 (0.49) | PTGES | |
| SCHEMBL3578734 | 0.85 | PTGES (0.50) | PTGESGAATHRBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | PTGES 35/4885GFER 3076/4885GALR3 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.