Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662786 | 0.86 | KDM4E (0.48) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL5662784 | 0.86 | KDM4E (0.48) | ALDH1A1GAAKDM4EPKMHRH3 | |
| Hydrochloric Acid SCHEMBL23803344 | 0.85 | KDM4E (0.47) | ALDH1A1GAAKDM4EPKMHRH3 | |
| Hydrochloric Acid SCHEMBL23803348 | 0.85 | KDM4E (0.47) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL19582185 | 0.84 | KDM4E (0.46) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL19582184 | 0.84 | KDM4E (0.46) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL19204364 | 0.83 | KDM4E (0.50) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL15241329 | 0.82 | LMNA (0.52) | ALDH1A1GAAHRH3MAPK1CYP1A2 | |
| SCHEMBL13538389 | 0.81 | KDM4E (0.49) | ALDH1A1GAAKDM4EPKMHRH3 | |
| SCHEMBL12354522 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EPKMHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171724-A1 | Phosphonate Derivatives of Mycophenolic Acid | GILEAD SCIENCES, INC. (US) | 2008-07-17 | — | — | US | disclosed |
| EP-1809277-A2 | PHOSPHONATE DERIVATIVES OF MYCOPHENOLIC ACID | GILEAD SCIENCES, INC. (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006047661-A2 | PHOSPHONATE DERIVATIVES OF MYCOPHENOLIC ACID | GILEAD SCIENCES, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171724-A1 | Phosphonate Derivatives of Mycophenolic Acid | PPP5C, DUSP15, DUSP4 | ALDH1A1 3424/4885GAA 3296/4885KDM4E 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.