Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921884 | 0.93 | CXCR4 (0.52) | CCR5MEN1KMT2AOPRM1CHRM3 | |
| SCHEMBL4921834 | 0.92 | UBE2M (0.48) | CCR5MEN1KMT2AOPRM1CHRM3 | |
| SCHEMBL4927352 | 0.91 | MEN1 (0.56) | MEN1KMT2AOPRM1CHRM3CHRM2 | |
| SCHEMBL4920240 | 0.90 | ACKR3 (0.49) | CHRM3ALDH1A1LMNA | |
| SCHEMBL4923509 | 0.87 | CHRM3 (0.51) | CCR5MEN1KMT2AOPRM1CHRM3 | |
| SCHEMBL4915742 | 0.87 | HRH3 (0.47) | MEN1KMT2AOPRM1CHRM2HRH3 | |
| SCHEMBL4924921 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1HRH3LMNASMN1; SMN2 | |
| SCHEMBL4922893 | 0.86 | CCR5 (0.45) | CCR5CHRM3LMNASMN1; SMN2UBE2M | |
| SCHEMBL4922824 | 0.85 | TSHR (0.55) | CCR5MEN1KMT2AOPRM1CHRM3 | |
| SCHEMBL4921326 | 0.85 | UBE2M (0.49) | MEN1KMT2AOPRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | CCR5 4/4885MEN1 2193/4885KMT2A 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.