Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30176681 | 0.81 | DAO (0.45) | TAS2R8TSHRHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL17825003 | 0.74 | PARG (0.56) | MEN1KMT2ATSHRHTTPOLB | |
| SCHEMBL23997303 | 0.73 | LMNA (0.64) | MEN1CYP1A2KMT2ATSHRHTT | |
| SCHEMBL17807864 | 0.72 | BRD4 (0.58) | BRD4 | |
| SCHEMBL23119711 | 0.72 | LMNA (0.62) | MEN1CYP1A2KMT2ATSHRHTT | |
| SCHEMBL2762074 | 0.72 | LMNA (0.81) | MEN1CYP1A2KMT2ATSHRHTT | |
| SCHEMBL4522117 | 0.72 | MEN1 (0.61) | MEN1CYP1A2KMT2ATSHRHTT | |
| SCHEMBL1279621 | 0.71 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL23119670 | 0.71 | LMNA (0.57) | MEN1CYP1A2KMT2ATSHRHTT | |
| SCHEMBL2313078 | 0.71 | LMNA (0.50) | MEN1CYP1A2KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | ICAGEN, INC. (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | TRPV3, SCN3A, TRPV1 | TAS2R8 2665/4885MEN1 4328/4885CYP1A2 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.