Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913819 | 0.97 | ALDH1A1 (0.57) | ALDH1A1GAAPOLBATMSMN1; SMN2 | |
| SCHEMBL4924861 | 0.97 | ALDH1A1 (0.57) | ALDH1A1GAAPOLBATMSMN1; SMN2 | |
| SCHEMBL4920726 | 0.93 | LMNA (0.50) | ALDH1A1GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL4924890 | 0.92 | SMN1; SMN2 (0.49) | ALDH1A1GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL4924123 | 0.92 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBATMSMN1; SMN2 | |
| SCHEMBL4916484 | 0.90 | SMN1; SMN2 (0.47) | ALDH1A1GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL4923478 | 0.89 | ALDH1A1 (0.55) | ALDH1A1GAAPOLBATMSMN1; SMN2 | |
| SCHEMBL4915837 | 0.89 | ALDH1A1 (0.55) | ALDH1A1GAAPOLBATMSMN1; SMN2 | |
| SCHEMBL4923881 | 0.89 | LMNA (0.49) | ALDH1A1GAAPOLBSMN1; SMN2LMNA | |
| SCHEMBL4924914 | 0.89 | LMNA (0.49) | ALDH1A1GAAPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | ALDH1A1 1255/4885GAA 4442/4885POLB 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.