Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916712 | 0.90 | PPARG (0.44) | PPARGPPARATP53MAPT | |
| SCHEMBL333775 | 0.83 | PPARG (0.48) | PPARGPPARASCN9A | |
| SCHEMBL4916822 | 0.83 | PPARG (0.47) | PPARGPPARASCN9A | |
| SCHEMBL4927867 | 0.81 | TP53 (0.40) | PPARGPPARATP53MAPT | |
| SCHEMBL333600 | 0.79 | LMNA (0.48) | PPARGPPARASCN9AMAPTHTT | |
| SCHEMBL4914755 | 0.78 | PPARG (0.45) | PPARGPPARASCN9A | |
| SCHEMBL333599 | 0.77 | LMNA (0.50) | PPARGPPARASCN9AMAPTHTT | |
| SCHEMBL333764 | 0.76 | PPARG (0.42) | PPARGPPARASCN9A | |
| SCHEMBL4700830 | 0.76 | MCHR1 (0.38) | PPARGPPARATP53KCNH2 | |
| SCHEMBL4228522 | 0.75 | PTGES (0.59) | SCN9ASCN7AKCNH2SCN5ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | PPARG 2586/4885PPARA 3339/4885SCN9A 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.