Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710520 | 0.95 | APP (0.55) | APPCYP1A2PDE2APDE3BPDE3A | |
| SCHEMBL5681747 | 0.95 | APP (0.55) | APPCYP1A2PDE2APDE3BPDE3A | |
| SCHEMBL10208641 | 0.84 | APP (0.64) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL5710642 | 0.82 | APP (0.54) | APPCYP1A2PDE3BPDE3AP2RY12 | |
| SCHEMBL3104713 | 0.82 | APP (0.55) | APPCYP1A2 | |
| SCHEMBL10167845 | 0.81 | APP (0.68) | APPCYP1A2 | |
| Gamma-Aminobutyric Acid SCHEMBL21043922 | 0.81 | APP (0.71) | APPCYP1A2 | |
| Hexanoate SCHEMBL21043913 | 0.80 | APP (0.70) | APPCYP1A2 | |
| Octanoic Acid SCHEMBL21043903 | 0.79 | APP (0.68) | APPCYP1A2 | |
| Decanoic Acid SCHEMBL6708176 | 0.79 | APP (0.68) | APPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139404-A1 | Residual Enzyme Assays | NOVOZYMES A/S (DK) | 2008-06-12 | — | — | US | disclosed |
| EP-1756294-A1 | RESIDUAL ENZYME ASSAY | Novozymes A/S (DK) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005121353-A1 | RESIDUAL ENZYME ASSAY | NOVOZYMES A/S (DK) | 2005-12-22 | — | — | WO | disclosed |